BIO Asia–Taiwan 2023 亞洲生技大會

BIO Asia–Taiwan 2023 亞洲生技大會

講師

巨生生醫股份有限公司

 

Company Info

Name /MegaPro Biomedical Co. Ltd.

Address /10F-1, No.66, Shengyi 5th Rd., Zhubei City, Hsinchu County, Taiwan

Website /www.megaprobio.com

Presenter

Name /Shian-Jy Wang

Title /President

Email /jassywang@megaprobio.com

Telephone /03-5910360 ext.210

Fax /

Mobile /0933-949215

Company Type

Biotechnology

About the Company

MegaPro was founded in 2015 by a nanomedicine professional team. We are a clinical-stage specialty pharmaceutical company and focused on nanomedicine development. Two proprietary technology platforms have been developed including PEGylated Iron Oxide nanoparticles (IOP Injection) and polymer based nano formulation. According to the key features of the IOP Injection, MPB1514 and MPB1523 are developed and completed the phase 2 clinical study. Regarding the second platforms which is polymer based nano formulation, MPB-1734 is developed and currently under phase1/2a clinical study.

Brief Description of main products or services

MPB-1514 An intravenous (iv) iron for the treatment of Iron Deficiency Anemia (IDA)

  • Non-dextran based preparations to avoid hypersensitivity caused by dextran.
  • Lowest labile iron and oxidative stress to avoid inflammation.
  • Highest macrophage uptake efficiency thus to produce higher Ferritin and Transferrin saturation.
  • Lowest iFGF23 elevation to avoid severe hypophosphatemia and long term inflammation.

MPB-1523 A liver-specific MRI contrast agent

  • Higher r2 relaxivity
  • High macrophage uptake efficiency
  • Low free iron release
  • Low oxidative stress generated
  • Non-sugar base formulation, Low risk for hypersensitivity,

MPB-1734 505(b)(2) new drug for solid tumor

  • Improved safety (hypersensitivity), >1000 x solubility increased
  • Better drug targeting to tumor by nanosized particle
  • Reduction of major dose-limiting side effect
  • Synergistic benefit in combination with immuno-oncology agents

Contact Person

Name /Mark Chiu

Email /markchiu@megaprobio.com

Phone /+886-3-5910360 ext.220