2020台灣生技月 Bio Taiwan 生物科技大展

2020 台灣生技月 南港展覽館

講師

Nozomu Kamiya

Session 7 – AI for Therapeutic Innovations
Date: 23 July (Thursday) 12:20 – 13:50 (GMT+8)
Venue: 701EF, 7F, TaiNEX2 / Online event platform


Nozomu Kamiya

Director
FUJITSU LIMITED


● March 1991: Graduated from Department of Chemistry, Faculty of Science, Hokkaido University
● March: 1993 Completed master's degree at Department of Chemistry, Graduate School of Science, Hokkaido University
● April 1993: Joined Fujitsu Limited and had worked for software development for computational chemistry
● June 2004 Got into Bio-IT Business Development Unit when Fujitsu establish it and was engaged in a drug discovery information project
● April 2012: Appointed manager of In silico Drug Discovery Research Division, BioIT Business Development Unit
● April 2015: Appointed Director of Bio-IT R&D Office, Research & Development Division, Next-Generation Healthcare Innovation Center
● July 2016: Received Ph.D. degree from Department of Advanced Interdisciplinary Studies, Graduate School of Engineering, the University of Tokyo
● Present: Director, Research & Development Division, Healthcare Solutions Unit​​

Speech title & Synopsis

Introduction of IT-based Drug Discovery (tentative)

Fujitsu is working on "IT-based drug discovery" to create novel drug candidates with computer. In this presentation, a practical example of designing small molecule inhibitors against CSF-1R (Colony Stimulating Factor-1 Receptor) with an original abstract fragment based de novo design approach and molecular dynamics simulation will be shown, together with a technology related to force field parameters which describes shape of molecules precisely. Further, a practical example of conformation analysis of Cyclosporin A with a new conformation analysis technology will be shown since drug discovery in middle sized molecules such as cyclic peptides is an attracting area for their particular properties against small molecules or antibodies, and it is known that the properties of a cyclic peptide depend on its conformation.