Plenary Session – Global Development in Biotechnology
Date: 24 July (Wednesday) 9:00 – 12:05 Venue: 3F, Bldg. A, CTBC Financial Park, Ballroom A
Professor of Medicine
Harvard Medical School & MIT
Brigham and Women’s Hospital
Dr. Jeff Karp is a Professor of Medicine at Brigham and Women’s Hospital, Harvard Medical School. He is also a principal faculty member at the Harvard Stem Cell Institute, and an affiliate faculty member at the Broad Institute and at the Harvard-MIT Division of Health Sciences and Technology.
He works in the fields of drug delivery, medical devices, stem cell therapeutics, and tissue adhesives. He has published over 125 peer-reviewed papers, with >17,000 citations, and has given over 300 invited lectures. He has over 100 issued or pending national and international patents. Several technologies developed in his lab have led to multiple products currently in development or on the market and for the launch of seven companies that have raised over $180 million in funding. Technologies include hightech skincare, tissue adhesives and 3D printed biomedical devices, immunomodulation with bioligically responsive materials, small molecule regenerative therapeutics with an initial target of hearing loss, cannabinoid therapeutics, and biomedical devices to improve child safety.
Karp has received over 50 awards and honors. Boston Magazine recently recognized Karp as one of 11 Boston Doctors Making Medical Breakthroughs. The Boston Business Journal recognized him as a Champion in Healthcare Innovation and MIT’s Technology Review Magazine (TR35) also recognized Karp as being one of the top innovators in the world. His work has been selected by Popular Mechanic's as one of the Top 20 New Biotech Breakthroughs that Will Change Medicine. He gave a TEDMED talk at the Kennedy Center in DC on bioinspired medical innovation, and since 2015 has been a member of the TEDMED Editorial Advisory Board. In 2015 and 2016, he received Breakthrough Awards from the Kenneth Rainin Foundation, and in 2015 was a commencement speaker at the University of Toronto Faculty of Dentistry and Pharmacy. His lab has been funded by the NIH, NFL, Bill and Melinda Gates Foundation, Prostate Cancer Foundation, Kenneth Rainin Foundation, JDRF, Helmsley Trust, DoD, Sanofi, J&J, Phillips, Leo Pharma, UCB Pharma. Rheumatology Research Foundation, Coulter Foundation, American Heart Association, Deshpande Foundation. In 2018 Karp gave a TEDx talk on Radical Simplicity at Boston’s JFK Museum. Session Speech Title & Synopsis: Towards Acclerated Medical Innovation
When developing technologies to solve medical problems, often one encounters significant hurdles, that at times seem insurmountable. Overcoming these hurdles requires new ways of thinking. One approach is to turn to nature for inspiration. Millions and millions of years of research and development at our fingertips, and all we need to do is look outside to the amazing creatures that inhabit our planet. This talk will explore medical technologies being developed that harness lessons from nature for inspiration, from creatures such as geckos, spider webs, jellyfish, porcupine quills, snails, to spiny headed worms. Another approach is radical simplicity — the art and discipline of reducing a problem to its essence. These tools has been harnessed to develop a small molecule therapeutic for functional restoration of hearing (just completed a US FDA Phase I/II trial), next generation tissue adhesives (CE Mark in EU) and therapeutic strategies to combat inflammatory bowel disease and arthritis that are advancing towards clinical studies. This talk opens new paths to the continual innovation that is so important in our fast-changing world.